The following is a summary of “Rate of change in upper and lower motor neuron burden is associated with survival in amyotrophic lateral sclerosis,” published in the April 2025 issue of Journal of ...

Patients do not typically transition to an upper motor neuron bladder or bowels Bladder and bowel anal-rectal sphincter remains flaccid, becomes highly complaint and is characterized by underactivity ...

Patients with primarily lower motor neuron findings often receive conflicting opinions as to what their disorder represents, as the absence of signs of upper motor neuron dysfunction is ...