Research studies in cardiovascular epidemiology assessing the relationship between a primary exposure and a health outcome must account for the presence of what are often called third variables, ...

BACKGROUND: In the phase 3 randomized controlled study ATTRibute-CM (Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy), acoramidis, a transthyretin stabilizer, ...

There is limited evidence on the safety of antiplatelet therapy in acute ischemic stroke (AIS) patients with thrombocytopenia, 6 particularly regarding antiplatelet strategy and the varying severity ...

BACKGROUND: Evaluation of whether dyspnea has a cardiac cause is essential. Guidelines from 2016 were reported to result in a ...

The present study was a retrospective observational study based on a nationwide Japanese administrative case‐mix Diagnostic Procedure Combination (DPC) database, the Japanese Registry of All Cardiac ...

Environmental toxicants and pollutants are causes of adverse health consequences, including well-established associations between environmental exposures and cardiovascular diseases. Environmental ...

Guideline-directed medical therapies and guideline-directed nonpharmacological therapies improve quality of life and survival in patients with heart failure (HF), but eligible patients, particularly ...

Left ventricular (LV) systolic function is a powerful prognosticator of clinical outcome following percutaneous coronary intervention (PCI), 1, 2, 3 and patients who do not have in‐hospital LV ...

While significant progress has been made in reducing disparities within the US health care system, notable gaps remain. This article explores existing disparities within pediatric congenital heart ...

Patient engagement is essential for virtual HF programs designed to optimize GDMT. 8 Digital health has the potential to expand such programs to focus on activating patients to advocate for optimal ...

Independent of etiology, hemolytic diseases are associated with thrombosis, inflammation and immune dysregulation, all together contributing to organ damage and poor outcome. Beyond anemia and the ...

BACKGROUND: Anthracycline-induced cardiotoxicity has a variable incidence, and the development of left ventricular dysfunction is preceded by elevations in cardiac troponin concentrations.