But in 2008, Mukherjee stumbled across a new and much faster way to cause intracellular mayhem. Studying bacterial interactions with actin ... shielded from the onslaught of white blood cells, ...

Antibodies are best known for their ability to latch onto and neutralize bacteria, viruses and other pathogens. But these ...

Antibodies are best known for their ability to latch onto and neutralize bacteria, viruses and other pathogens. But these immune proteins can do more than that: They also activate other components of ...

Innovative delivery systems allow recombinant antibodies to precisely access intracellular targets ... Alternative Hosts: Bacteria, yeast, and plant-based systems are optimized to enhance cost ...

Libera Bio is working to unlock those targets using nanotechnology that has been proven to enable intracellular delivery of whole antibodies and other payloads. Libera Bio’s solution to the ...

First described for rickettsiae, the plaque assay methods have been adapted to other intracellular bacterial pathogens. There is no single model, thus each assay should be refined depending on the ...

TNF-α is a potent inducer of the inflammatory response, a key regulator of innate immunity and plays an important role in the regulation of Th1 immune responses against intracellular bacteria and ...

When a bacterium enters a cell’s cytoplasm, intracellular lipid droplets close in, bringing with them an arsenal of antimicrobial proteins, the research shows. “This is the first evidence that there’s ...

Yale scientists have discovered a promising way to trigger immune responses against certain tumors, using a lupus-related antibody that ... that binds to intracellular RNA activates cGAS-mediated ...