Tandem mass spectrometry is a powerful tool in proteomics. By ionizing peptides and then fragmenting those ions into smaller product ions, researchers can determine the biomolecules’ amino acid ...

Effective protein characterization depends on the precise isolation and fragmentation of peptide ions within the mass spectrometer, typically coupled with liquid chromatography (LC-MS/MS). In a ...

For glycopeptide characterization, mass spectrometry has arisen as the go-to methodology. As well as the instrumental arrangement, a suitable software solution is essential to enable glycopeptide ...

This is the fourth and final article in the series, describing the characterization of protein-based bio-therapeutics by bottom-up analysis at the peptide level (peptide-mapping analysis). This ...

Electron ionization (EI) is a hard ionization method that is typically used with gas chromatography-mass spectrometry (GC-MS). The mass spectral fragmentation patterns generated by EI are used for ...

After three years of development, the National Institute of Standards and Technology (NIST) has released a major upgrade of the widely used NIST/EPA/NIH Mass Spectral Library. The library is an ...

Nanomaterials have become widely used in several applications across industry and research, such as chemical synthesis, catalysis, anti-bacterial coatings, many others. Many of the physical properties ...