A 40-year-old man with cystic fibrosis (CF) (F508del/F508del) attended his routine annual review at the regional adult CF ...
Introduction The clinical relevance of ventilation patterns identified by MRI in severe asthma and the degree to which they ...
Background Hospitalisation due to acute exacerbations of COPD (AECOPD) is common, and subsequent mortality high. The DECAF score was derived for accurate prediction of mortality and risk ...
Correspondence to Professor Claire L Shovlin, Professor of Practice (Clinical and Molecular Medicine), NHLI Vascular Science, Imperial College London, Imperial Centre for Translational and ...
Prognostic performance of the RAPID risk stratification score in pleural infection: a systematic review and meta-analysis ...
Background The role of interleukin 17 (IL-17) in hypoxic pulmonary hypertension (HPH) remains unclear. This study is designed to explore whether IL-17 is a potential target for HPH treatment. Methods ...
Introduction Development of novel treatments for cough and its management are hampered by the lack of well validated objective cough frequency methodologies. Previous validations have been performed ...
Oral montelukast in acute asthma exacerbations: a randomised, double-blind, placebo-controlled trial
1 Department of Respiratory Medicine, Norfolk & Norwich University Hospital, Norwich, UK 2 School of Medicine Health Policy & Practice, University of East Anglia, Norwich, UK Correspondence to Dr ...
Rationale Advanced fibrosing interstitial lung disease (ILD) is often progressive and associated with a high burden of symptoms and poor prognosis. Little is known about the symptom prevalence and ...
Introduction and Aim The efficacy and safety of nintedanib in patients with IPF were assessed in two replicate Phase III placebo-controlled INPULSIS trials. In both trials, nintedanib reduced disease ...
Background: TORCH (Towards a Revolution in COPD Health) is an international multicentre, randomised, placebo-controlled clinical trial of inhaled fluticasone propionate/salmeterol combination ...
Introduction Current bronchiectasis guidelines advise against the use of inhaled corticosteroids (ICS) except in patients with associated asthma, allergic bronchopulmonary aspergillosis (ABPA) and/or ...
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