Background Idiopathic pulmonary fibrosis (IPF) is a disease of progressive lung scarring. There is a known association ...

Background Bronchoalveolar lavage (BAL) is essential in determining the efficacy of novel therapies in alpha-1 antitrypsin deficiency (AATD). These require initial proof-of-concept demonstration that ...

Background The evidence base on montelukast-associated adverse outcomes is inconclusive in children and young persons (CYP) with asthma. We aimed to investigate 1-year incidence of neuropsychiatric ...

Background Severe asthma is a chronic lung disease characterised by inflammation, airway hyperresponsiveness (AHR) and airway remodelling. The molecular mechanisms underlying uncontrolled airway ...

Atypical radiological manifestation of sarcoidosis presenting with an anterior mediastinal mass ...

Correspondence to: Professor J A Wedzicha Royal Free and University College Medical School, London NW3 2PF, UK; j.a.wedzicha{at}medsch.ucl.ac.uk Although it was clearly rational to increase the ...

Environmental factors, here taken to include pollutants, lifestyle factors and behaviours, can play an important role in serious, chronic pathologies with large societal and economic costs, including ...

Introduction Chronic rhinosinusitis with nasal polyposis (CRSwNP) affects a significant proportion of people with severe asthma (SA). Despite the effectiveness of anti-IL5/5R therapies in the ...

12 Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada Correspondence to Dr Wan C Tan, UBC James Hogg Research Centre, Providence Heart+Lung Institute, University of ...

2 Institute of Respiratory Medicine, University of Sydney, NSW, Australia 3 South Western Sydney Clinical School, University of New South Wales, NSW, Australia Background: Sahaja Yoga is a traditional ...

8 Biometrics, Late-stage Development, Respiratory and Immunology, BioPharmaceuticals RandD, AstraZeneca, Cambridge, UK 9 Late-stage Development, Respiratory and ...

Background Patient perception of asthma treatment is rarely captured, and no specific tools exist to measure it. We developed an inhouse severe asthma patient feedback questionnaire (SAPFQ) using ...