The San Francisco 49ers delivered a statement performance under the lights in Indianapolis, rolling past the Colts with a ...

With six receptions and 146 yards from scrimmage, McCaffrey registered his 54th career game with at least five receptions and ...

FB Kyle Juszczyk, TE George Kittle, RB Christian McCaffrey, T Trent Williams, LB Luke Gifford, and LS Jon Weeks were selected ...

The San Francisco 49ers entered Monday night having already clinched a playoff berth, but their win in Indy reflected a team ...

Get an inside view of the 49ers locker room following the team's Week 16 win over the Colts presented by Ticketmaster.

San Francisco 49ers QB Brock Purdy, TE George Kittle, RB Christian McCaffrey, T Trent Williams, and LB Dee Winters ...

San Francisco 49ers head coach Kyle Shanahan reflected on the 49ers journey this season, emphasizing consistency, leadership, ...

The San Francisco 49ers finished their Week 16 "Monday Night Football" contest with a 48-27 win over the Indianapolis Colts at Lucas Oil Stadium.

San Francisco 49ers DL C.J. West reflected on his first-career sack and shared his reaction to the 49ers "Monday Night ...

San Francisco 49ers TE George Kittle secured an 11-yard touchdown reception from QB Brock Purdy, giving the 49ers momentum ...

San Francisco QB Brock Purdy throws his fourth touchdown of the night to WR Jauan Jennings. San Francisco 49ers QB Brock ...

San Francisco 49ers RB Christian McCaffrey catches a 2-yard touchdown pass from QB Brock Purdy in the team's Week 16 matchup ...