Medically reviewed by Jeffrey S. Lander, MD ATTR-CM is an acronym for the medical condition called transthyretin amyloid cardiomyopathy. There are two causes of ATTR-CM, an inherited gene mutation and ...

Hereditary transthyretin amyloidosis (hATTR) with polyneuropathy is a rare disorder passed down in families that gets worse over time. It’s a result of a change in a gene, also called a mutation.

Among members of the Richardson family who carry a mutation in the PSEN1 gene, the average age when symptoms start is 39.

Reiswig, like many members of his family, carries a mutation in a gene called presenilin-2, which causes his brain to overproduce amyloid plaques.

Voyager Therapeutics presents data on tau silencing therapy VY1706 and anti-amyloid therapy at ASGCT 2025.

Wainua is an injectable medicine. Here’s how it treats hereditary transthyretin-mediated amyloidosis (hATTR).

Scientists are just beginning to understand the microbes that have been with us for millennia — the so-called microbiome, ...

The new understanding of molecular events that drive the various forms of amyloidosis has generated treatment strategies that depend on early diagnosis to reduce fatal outcomes.

- Featured data also include anti-amyloid gene therapy for Alzheimer’s disease, as well as multiple presentations on Voyager’s continued enhancements to its highly BBB penetrant novel capsids - ...

However, the main concern with anti-amyloid therapy is what doctors call amyloid-related imaging abnormalities, or ARIA—usually small spots of swelling or blood in the brain tissue.

ATTR amyloidosis is related to the abnormal production and buildup of a type of amyloid called transthyretin. Learn about symptoms, diagnosis, and treatments.

A new dosing regimen for Kisunla, to help lower the risk of certain side effects, has been approved by the U.S. Food and Drug ...