Researchers have dosed the first participant in a clinical trial of an investigational medicine designed to lower the amount ...

RIKEN researchers have demonstrated the protective effects of a specific genetic mutation against Alzheimer's disease in ...

A micrograph showing inflammatory responses in the cortex of the new model mouse. Alzheimer's disease patients and mouse ...

Amyloid-β is a fragment of a larger protein called amyloid precursor protein (APP ... mainly because gene-association studies strongly implicate microglia in sporadic Alzheimer’s disease.

Researchers have developed a tau-targeting vaccine that could help prevent the progression of Alzheimer’s disease by ...

Researchers hope to launch human clinical trials in their quest for a vaccine to prevent the buildup of pathological tau after demonstrating that this vaccine generated a robust immune response in ...

A single injection of Alnylam’s RNA interference candidate ALN-APP – which is designed to switch off the production of amyloid precursor protein ... shown to achieve gene silencing in the ...

An experimental vaccine that blocks Alzheimer's-related tau protein buildup has generated a robust immune response in both ...