As the Bills face off against the 49ers in Week 13, their defense looks to get a noticeable boost, as the team activated LB ...

Defeating the Buffalo Bills on the road will be extremely difficult for the San Francisco 49ers. Going to the East Coast when ...

The Bills also announced that they are elevating quarterback Mike White and tight end Zach Davidson from the practice squad.

The table is set for the Bills to clinch a fifth consecutive AFC East title in prime time on WGRZ-TV. Expect them to deliver.

The Buffalo Bills have opened the 21-day practice windows of offensive tackle Tylan Grable and defensive tackle DeWayne ...

The Bills will not have one of their key offensive players for Sunday’s game against the 49ers, though they could get one of ...

Former Buffalo Bills defensive end Leonard Floyd spoke about facing his old team on Sunday night with the San Francisco 49ers ...

Buffalo activated linebacker Matt Milano off injured reserve on Saturday, giving the Bills defense a big boost ahead of ...

Josh Allen is currently the frontrunner in NFL MVP odds, and we expect the Bills superstar quarterback to use his athleticism ...

San Francisco played without four key players - quarterback Brock Purdy, left tackle Trent Williams, defensive end Nick Bosa ...

At 9-2, the Buffalo Bills have surpassed any reasonable expectations set for the team coming into the season. A fifth ...

The Game Matchups Preview series is dedicated to breaking down how the Buffalo Bills match up with their opponent in every ...