Cell crowding causes high-grade breast cancer cells to become more invasive by activating a molecular switch that causes the cells to shrink and spread.

Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the 'powerhouses' of our cells, allows us to make the fuel we need from sugars, a ...

These events are associated with innate training and can have long-term impacts on hematopoietic stem and progenitor cell (HSPC) development but can also compromise their function. While many ...

Several autophagy pathways operate within a cell, including macroautophagy, microautophagy and chaperone-mediated autophagy. Liver fibrosis is a consequence of the sustained inflammatory processes ...

Facundo’s lab studies B-cell biology and antibody responses, particularly B-cell receptor signaling dynamics, involvement of the cortical cytoskeleton, and more recently the role of B-cell metabolism.

Plant responses to light are multiple. Light is an energy source, converted to sugars by photosynthesis. It is also a signal sensed by specific photoreceptors for red, blue and UV-B radiation ...

How alterations in cell metabolism translate into specific developmental gene programs remains a major question. This study ...