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C&EN23d
Probing the Coupled Equilibria between Metal Nanoparticles, Antibiotics and Components of the Extracellular Matrix in Biofilms with SERS
In the case of biofilms, the nature of the extracellular matrix makes SERS methods particularly challenging since it is chemically complex, contains multiple constituents known to interact strongly ...
gut.bmj24d
Reversal of pancreatic desmoplasia by a tumour stroma-targeted nitric oxide nanogel overcomes TRAIL resistance in pancreatic tumours
This study aimed to develop a TRAIL-based nanotherapy that not only eliminated the extracellular matrix barrier to increase TRAIL delivery into tumours but also blocked antiapoptotic mechanisms to ...
eLife1mon
Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines
Invitrogen Cat# MA137493 Detects cartilage matrix in immunofluorescence (1:200) Antibody Anti-Collagen I (Rabbit monoclonal) Abcam Cat# ab138492 Used for extracellular matrix immunostaining (1:200) ...
Frontiers1y
Microscale tissue engineering of liver lobule models: advancements and applications
These liver lobules represent the fundamental architectural and functional units of the liver and exhibit a complex microenvironment that can be broadly categorized into two components: cells and ...
Frontiers1y
Fibroblast-derived matrix models desmoplastic properties and forms a prognostic signature in cancer progression
Stromal-derived extracellular matrix (ECM) is significantly altered in desmoplasia ... The raw files were analyzed using Proteome Discoverer 2.4. Label-free quantitation (LFQ) was enabled in the ...
ahajournals.org6y
Vitamin K–Dependent Matrix Gla Protein as Multifaceted Protector of Vascular and Tissue Integrity
Step 4: p-cMGP is secreted into the extracellular matrix or the circulation to inhibit soft tissue calcification, VSMC (vascular smooth muscle cell) trans-differentiation into OPC (osteochondrogenic ...