Schizophrenia is a highly heterogeneous psychiatric disorder affecting ~1% of the global population, typically emerging in ...

A comprehensive genetic investigation led by Dr. Feng Liu at Tianjin Medical University General Hospital has uncovered striking molecular connections between schizophrenia and bone health, identifying ...

Genomic analysis across 14 psychiatric disorders reveals extensive shared genetic architecture, challenging diagnostic ...

Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

Discover the innovative TECHNO platform for full-length gene humanisation, enhancing models for human gene function.

Researchers at The University of Tokyo developed TECHNO, a two-step genome editing strategy that replaces entire mouse loci with human genomic DNA. The method integrates fragments over 200 kbp.

Uterine fibroids (UFs) are common hormone-dependent tumors with a complex etiology involving both genetic and environmental factors. This study aimed to investigate, for the first time, the ...

Uncovering how rare genetic changes disrupt brain signaling and structure, this landmark study sheds new light on the roots of schizophrenia and opens doors for future therapies. Study: Whole-exome ...