A drug candidate, previously successful at treating severe fatty liver disease, reduces atherosclerosis - a primary driver of cardiovascular death worldwide - in large mammals, a study suggests.

Citation: Preventing harmful protein aggregation: Synthetic peptides as the basis for multifunctional drugs in Parkinson's disease (2025, April 24) retrieved 28 April 2025 from https://phys.org ...

Scientists have identified five specific blood proteins that can accurately predict a person's risk for developing a serious ...

In Alzheimer's, Parkinson's, and type 2 diabetes, harmful protein aggregates and deposits, known as amyloid plaques, develop. There is also much evidence that these three diseases are ...

A drug candidate, previously successful at treating severe fatty liver disease, reduces atherosclerosis — a primary driver ... in part by reducing signaling from the NLRP3 "inflammasome" protein, ...

Recent research has unveiled that specific blood proteins can indicate an individual's risk of developing severe liver disease up to 16 years prior to the onset of any symptoms. This groundbreaking ...

Kynurenines can affect feeding directly via glutamate receptors (NMDAr) in the brain and possibly via the G-protein coupled receptor GPR35. Fatty acid metabolism can affect inflammatory cytokine ...