IgG antibodies mediate inflammation and immunity through their effector functions. The Fc region of the IgG antibody mediates interactions between complement proteins and FcγR on myeloid and ...

FcRn protects IgG and albumin from catabolism, transports IgG across the placenta, and regulates IgG function. Blocking or augmenting FcRn can decrease autoimmune antibodies and enhance drug delivery.

Using eight bivalent potent antibody fragments, they found that all had lower neutralization than intact IgG antibodies against D614G. All eight had an even more precipitous drop against Omicron ...

Food-specific IgG was evaluated, and it was found that people indeed do make food-specific antibodies – specifically IgG. It was postulated that this is what accounted for the food sensitivities ...

Unlike IgG antibodies, which activate immune cells circulating in the blood, IgE antibodies bind very tightly to immune cells found in tissues.

Discover essential antibody purification methods, from affinity chromatography to ion exchange chromatography, for research ...

As therapeutic research moves toward more targeted, efficient, and scalable solutions, nanobodies—also known as VHH ...

Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents infection of Omicron lineages. Proceedings of the National Academy of Sciences, 2024; 121 (3 ...

Up to half of patients with NMOSD and AQP4-IgG have other detectable serum autoantibodies (e.g., thyroperoxidase, antinuclear, and Ro/SS-A antibodies), and one third have an autoimmune disease ...

Rubella antibodies in the blood mean that a person’s immune system has developed a response to the rubella virus. A positive result for rubella immunoglobulin (IgG) antibodies means a person is ...