AI models help pinpoint key neoantigens for personalized skin cancer vaccines

In a new study, University of Arizona researchers created a model for cutaneous squamous cell carcinoma, a type of skin ...
MedPage Today

FDA Approves Maintenance Combo for Small Cell Lung Cancer

The FDA approved lurbinectedin (Zepzelca) plus either atezolizumab (Tecentriq) or atezolizumab and hyaluronidase (Tecentriq Hybreza) as first-line maintenance therapy for extensive-stage small cell ...
ascopubs.org

Ifinatamab Deruxtecan in Patients With Extensive-Stage Small-Cell Lung Cancer: Primary Analysis of the Phase 2 IDeate-Lung01 Trial

Patients were randomized to receive I-DXd 8 or 12 mg/kg intravenously every 3 weeks (Q3W) in part 1 (dose optimization) and received I-DXd 12 mg/kg in part 2 (extension). The primary endpoint was ...
ascopubs.org

Role of Circulating Tumor DNA Tumor Fraction in Advanced Non–Small Cell Lung Cancer and Its Impact on Patient Treatment Outcomes: A Prospective Real-World Study

Artificial Intelligence–Powered Human Epidermal Growth Factor Receptor 2 Quantification and Clinical Outcomes in Human Epidermal Growth Factor Receptor 2–Positive Biliary Tract Cancer Treated With ...
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Two microbial metabolites compete to control the cells' protein building machinery

The microbiome-the trillions of bacteria, viruses, and fungi that live quietly in our body-plays a crucial role in shaping human health by providing a variety of micronutrients necessary for vital ...