Dravet syndrome (DS) is a rare and severe form of epilepsy that causes intellectual disability and motor deficits and can lead to premature death. A loss-of-function mutation in one copy of SCN1A, ...

On Thursday April 1, the Department of Biology hosted Niels Ringstad, professor in the Department of Cell Biology at the New ...

This paper explores how diverse forms of inhibition impact firing rates in models for cortical circuits. In particular, the paper studies how the network operating point affects the balance of direct ...

To aid ongoing efforts towards interneuron classification, to facilitate the exchange of information and to build a foundation for future progress in the field, we propose and publicly endorse a ...

In contrast, reversible suppression of PV interneuron activity in adulthood produces no lasting effects. These findings identify an activity-dependent sensitive period for prefrontal circuit ...