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The nuclear lamina (NL) is a proteinaceous network found beneath the inner nuclear membrane. The NL is linked to a number of dynamic cellular activities including chromatin organization, transcription ...
Progerin is targeted to the nuclear lamina, an ~14 nm-thick fibrillar structure (in mouse embryonic fibroblasts) located adjacent to the inner nuclear membrane (NM) ().In most somatic cells, the main ...
Objective Ménétrier's disease (MD) is a rare hypertrophic gastropathy characterised by giant rugal folds, hypochlorhydria, protein loss and a classic constellation of symptoms (nausea, vomiting, ...
It used to be believed that eating too much protein at once would go to waste (meaning whatever excess your body couldn’t fully utilize before digesting would be excreted as a compound called ...
Lamina-associated domains (LADs) are chromatin regions at the inner nuclear membrane that form a repressive environment for transcription. Here, a haploid genetic screen revealed that chromatin ...
“The centromere distribution for non-Rabl configuration is regulated independently by the CII-LINC complex and a nuclear lamina protein known as CROWDED NUCLEI (CRWN),” explained Sachihiro Matsunaga ...
Through their work, they found that protein complexes known as condensin ... The second step of the process is that the CRWNs stabilize the scattered centromeres on nuclear lamina within the nucleus.
Through their work, they found that protein complexes known as condensin ... The second step of the process is that the CRWNs stabilize the scattered centromeres on nuclear lamina within the nucleus.
Through their work, they found that protein complexes known as condensin II (CII) and protein complexes known as the linker of nucleoskeleton and cotoskeleton ... centromere distribution for non-Rabl ...
Kidney cells from those mice showed signs of nuclear membrane and chromatin breakdown. The cells had less nuclear lamina protein lamin B1, inner nuclear membrane protein lamin B receptor, and ...