Whenever you have a myeloma or cancerous cells, you have an imbalance. Your body, theoretically, makes 50% kappa light chain and 50% lambda light chain. Whenever you measure those two and you divide ...

The test we first mentioned, the “Serum Free Light Chain Assay” shows all this to your doctor from a blood sample. That is the diagnostic (figuring out what is wrong) part when it comes to… ...

For decades, the diagnosis of multiple myeloma required evidence of end-organ damage characterized by myeloma-defining events ...

Other symptoms of multiple myeloma include the following: Anemia: The overgrowth of myeloma cells in the bone marrow ...

An exclusive production of light chains can be found in ∼15% of myeloma cases, and in these light-chain multiple myeloma (LC-MM) cases, the phenotype remains unchanged throughout subsequent ...

Elevated immunoglobulin free light chain (FLC) level and abnormal FLC ratio are commonly seen in multiple myeloma (MM) and have prognostic implications. We hypothesized that presence of ...

In multiple myeloma, the relevant light chain production goes up but kappa goes up a lot more, says Singh, the study's corresponding author and Walter L. Shepheard Chair in Clinical Pathology at MCG.

Monoclonal free light chains (FLCs) frequently cause rapidly progressive renal failure in patients with multiple myeloma. Immunoassays which provide quantitative measurement of FLCs in serum, have ...

In all four patients with IgD myeloma, Singh found multiple bands that reflect both those dysfunctional antibodies and the excessive light chains characteristic of this type of multiple myeloma ...

Conoley, A. J., et al. (2025). Therapy-related B-lymphoblastic Leukemia Following Treatment for Multiple Myeloma with Unusual Surface Light Chain Expression: A Case Report.

Gail Whiteford wants to raise awareness of the symptoms she suffered to avoid the same happening to other people.

Acute renal failure is a frequent and serious complication in patients with multiple myeloma (MM). 1–3 Severe renal impairment is associated with a higher incidence of infections, particularly during ...