This study highlights the promising potential of LC–MS as a powerful tool for mAb quality control within the context of upstream processing.

Monoclonal antibodies ... Production methods depend on the type of mAb desired: Chimeric or humanized mAbs can be made by genetic manipulation and produced in mammalian, plant, or insect cells ...

In this review the focus is set on the biotechnological aspect of producing IgM class antibodies recombinantly in mammalian cells ... process for the production of a monoclonal antibody produced in a ...

The FDA plans to reduce and potentially replace animal testing for developing monoclonal antibody therapies and ... potential toxicities and defining cell lines using New Approach Methodologies ...

cells pre-complexed with AFM13, or acimtamig, a CD30/CD16A bispecific antibody, was safe and generated strong response rates for patients with refractory CD30-positive lymphomas, according to a ...

Antibodies are best known for their ability to latch onto and neutralize bacteria, viruses and other pathogens. But these immune proteins can do more than that: They also activate other components of ...

Automated tissue culture systems, like the SelecT automated mammalian cell culture system shown here, provide a level of plate-to-plate uniformity that can be difficult to achieve manually. And ...

midstream production of solar cells, downstream production of photovoltaic modules, and potentially other stages of the solar power supply chain. TOYO is well-positioned to produce high-quality solar ...

ADCs in Preclinical Development for the Treatment of B-cell Malignancies With the evolving ... Genetics), comprises a humanized anti-CD19 monoclonal antibody conjugated with MMAF using the ...

A bill to greatly expand efforts to lure film and TV production to Texas has passed the state Senate. The measure passed the upper chamber 23-8 on a strong bipartisan vote and now heads to the ...

Bispecific antibodies (bsAbs) are shaping the future of therapeutics ... and real-world case studies to help you tackle these hurdles. Discover how optimized production methods can deliver better ...