Micro decisions can have macro consequences. A soft matter physicist reveals how interactions within simple cellular ...

Researchers in Nikolaus Rajewsky's lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to map a tumor's cellular neighborhoods in 3D and identify potential targets ...

This study highlights lumican as a promising biomarker for predicting the onset and progression of diabetic nephropathy and reveals its close association with extracellular matrix remodeling, a ...

This study presents a novel in vitro 3D hepatocyte model that contains a nanofibrous scaffold designed to mimic the extracellular matrix (ECM) of the human liver, both structurally and biochemically.

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Single extracellular vesicle (EV) research holds the potential to revolutionize our ...

Given the contribution of EC-derived EVs to atherosclerosis, this model represents the first in vivo murine approach to tracking intercellular EC-EV communication within the plaque. It provides an ...