Myosin in muscles behaves in a unique way, which might explain why muscles have such strong contractile power. A cartoon showing the asymmetry in the weak binding between myosin and actin that biases ...

This achievement could aid in the hunt for new ways to treat diseases associated with myosin malfunction. ... Single-molecule imaging reveals how myosin moves to bring about muscle contraction.

At the molecular level, muscle contraction is defined by myosin molecules pulling actin filaments. New electron cryomicroscopy images with unprecedented resolution taken by researchers at Osaka ...

Myosin is also responsible for muscle contractions like your heartbeat that happens at regular intervals. Understanding Muscle Contractions ‌ Concentric Contractions .

Myosin is the molecular motor that powers muscle contraction as a result of conformational changes during its mechanochemical cycle. We demonstrate that the converter, a compact structural domain ...

We screened a small-molecule library for inhibitors of rabbit muscle myosin II subfragment 1 (S1) actin-stimulated ATPase activity. The best inhibitor, N-benzyl-p-toluene sulphonamide (BTS), an ...

Atomic images of muscle molecules in action have now been captured by researchers, giving possibility of new nanomachines. At the molecular level, muscle contraction is defined by myosin molecules ...

Experimental myosin inhibitor MT-125 sensitizes glioblastoma to radiation and kinase inhibitors, prolonging survival in mouse models.

In fact, jellyfish striated muscles also express the ancient "muscle myosin," but they lack several essential components that are characteristic for the structure and function of striated muscles ...

A potential treatment for glioblastoma crafted by scientists at The Wertheim UF Scripps Institute renders the deadly brain ...

Muscle myosin, whose study dates back to 1864, has served as a model system for understanding motility for decades. Kinesin, discovered [...] in 1985, is a relative newcomer by comparison.