A new hydrogel-based platform to preserve live patient-derived tumor tissues in the lab could pave the way for faster, more ...

Researchers have developed a bioengineered hydrogel platform capable of preserving patient-derived tumor tissues for longer ...

ISS-based lab-on-a-chip model advances the understanding of muscle aging and degeneration in microgravity, guiding future therapeutic strategies.

How plants maintain this precise positioning is unclear. Myosin XI is a plant-specific motor protein that moves along actin filaments and helps in intracellular organelle transport.

In both cases, AtNIP5;1 lost its polar localization, mirroring the results seen in the genetic mutants. These findings reveal a previously unknown role of myosin XI in boron acquisition in ...

An artificial intelligence safety firm has found that OpenAI's o3 and o4-mini models sometimes refuse to shut down, and will sabotage computer scripts in order to keep working on tasks.

The research, which has direct implications for how root systems manage responses to plant hormones, also has broader implications for understanding the condensation of other motile proteins that move ...

Figure 1. Single-molecule measurements of myosin dynamics using an optical tweezer system. (A–D) were modified from Hwang et al. (2021). (A) An actin-bead complex was interacted with a single myosin ...

Myosin VI is a unique reverse-directed motor protein in the myosin family. The D179Y mutation in Myosin VI is associated with deafness in mammals. This mutation destroys the processive motion of ...

Accurate control of macromolecule transport between nucleus and cytoplasm underlines several essential biological processes, including gene expression. According to the canonical model, nuclear import ...

eLife Assessment The authors present a useful agent-based model to study the tensile force generated by myosin mini-filaments in actin systems (bundles and networks); by numerically solving a ...