Uncovering the relationship between structure (connectivity) and function (neuronal activity) is a fundamental question across many areas of biology. However, investigating this directly in animal ...

Implantable bioelectronics are vital to neuroscience, neurological therapies, and brain-machine interfaces. They serve as ...

Parse Biosciences, the leading provider of accessible and scalable single cell sequencing solutions, today announced a groundbreaking study published in the journal Science that utilized Parse’s ...

This important study presents a new method for longitudinally tracking cells in two-photon imaging data that addresses the specific challenges of imaging neurons in the developing cortex. It provides ...

New research highlights how astrocytes, long considered mere support cells, actively shape brain network dynamics.

"Our previous studies found that the brain function for associative learning in C. elegans declines over time, and we thought this was due to a decline in neuronal activity with age," said Binta ...

Long overlooked and underestimated, glial cells—non-neuronal cells that support, protect and communicate with neurons—are ...

Here, we address this question further by combining large-scale electrophysiological recordings, to characterize the functional connectivity of developing neuronal networks in vitro, with a generative ...

Neurons that die early in Alzheimer’s help drive brain waste removal. Treating this process sooner could change outcomes.

Measuring neuronal voltage signals has traditionally been done through electrophysiology techniques. Highly skilled scientists can use glass electrodes when performing patch-clamp experiments to ...

(b) Photograph of neuronal networks. Neurons are separated by square areas, and these are connected through the microchannels. Credit: Adapted from Advanced Materials Technologies (2024).

Neuronal excitation triggers an influx of calcium into mitochondria, triggering transcription of mtDNA. Expression of oxidative phosphorylation components climbs, ramping up ATP. This coupling falters ...