Oligodendrocytes (the cells that produce myelin) and nerve fibers are also destroyed. 1–4 Most patients with multiple sclerosis have an initial relapsing–remitting course for 5 to 15 years ...

Now, in a study published in The Journal of Neuroscience, researchers tracked oligodendrocytes as they aged and found that mature oligodendrocytes survived longer following DNA damage and underwent a ...

Oligodendrocytes grown in thyroid hormone did not stain positively for NG2 or A2B5 (Figure 5A,B) indicating that these oligodendrocytes were mature. (Enlarge Image) Oligodendrocyte morphology .

Researchers discovered that oligodendrocytes, not just neurons, produce amyloid β in Alzheimer's disease, and suppressing their activity improves disease pathology. This finding suggests new ...

Three recent papers challenge that assumption, identifying another, unexpected source—oligodendrocytes. In the September Nature Neuroscience, scientists led by Klaus-Armin Nave at the Max Planck ...

Oligodendrocytes from later waves eventually replaced those generated in earlier waves, but if one wave was lost, the other waves could compensate.

Oligodendrocytes under Immune Attack Actively Harm Axons. The scientists could also identify a mechanism how oligodendrocytes attacked by T cells harm their axonal partners.

Oligodendrocytes sense and respond to the electrical signals. Now, a team of neuroscientists led by Aiman Saab at the Institute of Pharmacology and Toxicology at the University of Zurich ...

The new therapy, called PIPE-307, targets an elusive receptor on certain cells in the brain that prompts them to mature into myelin-producing oligodendrocytes. Once the receptor is blocked, the ...

Chemicals from 2 groups had an adverse effect on oligodendrocytes. Organophosphate flame retardants, which are commonly found in electronics and furniture, inhibited the generation of ...

“Loss of oligodendrocytes underlies multiple sclerosis and other neurological diseases,” said the study’s principal investigator, Paul Tesar, the Dr. Donald and Ruth Weber Goodman Professor of ...