Waldenstrom's macroglobulinemia—a condition that is characterized by overproduction of IgM antibodies and most commonly occurs in lymphoplasmacytic lymphoma—is often accompanied by nervous ...

One of the patients (Patient 2) had a dramatic response to treatment with the proteasome inhibitor bortezomib, and we hypothesized that the paraprotein may play a role in the pathophysiology of ...

The presence of an IgG kappa paraprotein in all three patients tested may suggest a pathogenic role of the paraprotein.

The level of miR-1246 (C) shows slight negative correlation with the paraprotein level. Paraprotein levels were only available for the MGUS and myeloma groups and were measured as either IgG or IgA.

Non-secretory myeloma is a rare form of myeloma. In people with this form, myeloma cells do not release an abnormal protein called paraprotein, making it harder to diagnose than other types of ...

There are different types of myeloma. Your type is named after the abnormal immunoglobulin (paraprotein) made by the myeloma cells.

The condition is usually detected incidentally when a routine check-up shows increased levels of paraprotein or free light chains in the blood or urine.

Sporadic late-onset nemaline myopathy with monoclonal paraprotein as a malignancy rather than disimmunity and treatment with chemotherapy-based approach.

Myeloma (also known as multiple myeloma or myelomatosis) is a blood cancer characterised by the proliferation and accumulation of abnormal plasma cells in the bone marrow and, in almost all cases, the ...

Patients with monoclonal gammopathy of undertermined significance must be monitored for malignant transformation or toxicity related to the presence of paraprotein (e.g., renal impairment, neuropathy) ...

A former RAF airman has won compensation after proving his incurable bone marrow cancer was caused by years of exposure to helicopter exhaust fumes. Zach Stubbings was diagnosed with a multiple ...

The stage of your myeloma tells your doctor about how it is affecting you and how it might develop. Doctors use the stage of your myeloma to help them decide on the best treatment for you.