Here, we assess the efficacy of XON7, a first-in-class glyco-humanized polyclonal antibody (GH-pAb), in preclinical models ... evidenced by caspase 8/9 activation, ROS generation, and mitochondrial ...

An investigational monoclonal antibody called bentracimab can safely and effectively reverse potentially catastrophic bleeding complications linked to ticagrelor, a common drug used to treat patients ...

The immune system produces anti-citrullinated protein antibodies (ACPAs) to target citrullinated proteins. ACPAs can help doctors diagnose early rheumatoid arthritis (RA) and predict how likely it ...

ASP3772 demonstrated a "similar or better" immune response measured by the level of antibody generation and their functional activity. Affinivax' shot performed better than Prevnar 13 against ...

Rising temperatures may not only affect physical health, but could also increase the burden of mental and behavioural disorders (MBD) like schizophrenia and depression by almost 50 per cent by ...

Here, we present the generation and characterization of a first-in-class fully human antibody targeting ACP-3, a tyrosine phosphatase produced by prostate epithelial cells. Compared to PSMA, ACP-3 is ...

Synthetic Design Lab Inc., which emerged from stealth with a $20 million seed round and a platform technology aimed at advancing the antibody-drug conjugate (ADC) space, began with its founders ...