A key feature that appears to facilitate neuroplasticity is the distinct nature of neurons compared to other cells.

A new study by Pitt researchers challenges a decades-old assumption in neuroscience by showing that the brain uses distinct transmission sites—not a shared site—to achieve different types of ...

These molecules travel across a microscopic gap called a synaptic cleft and bind to receptors on a neighboring postsynaptic neuron, triggering a response. Traditionally, scientists believed ...

At the synapse, neurons communicate chemically. When an action potential reaches the axon terminal, it triggers calcium influx, prompting vesicles to release neurotransmitters into the synaptic cleft.

Glutamate released into the synaptic cleft binds to NMDA and AMPA receptors leading to increased Ca 2+ entry resulting in an excitotoxic cascade. If not properly cleared, elevated levels of glutamate ...

Magenta arrowheads, postsynaptic membrane proteins with extracellular domains extending 13-14 nm into the synaptic cleft. Blue arrow, lateral matrix of macromolecules in synaptic cleft. Scale bar, 20 ...

Neuroscience Why GABA Is Important for Well-Being How the brain chemical works and why it’s important for your health. Posted May 6, 2024 | Reviewed by Gary Drevitch ...

Detecting synaptic clefts is a crucial step to investigate the biological function of synapses. The volume electron microscopy (EM) allows the identification of synaptic clefts by photoing EM images ...

Because of its full integration between computing power and memory, the synaptic transistor can achieve significantly higher energy efficiency and move data extremely fast, researchers wrote in ...

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