The arterial vasculature is the second most frequently calcified structure in the human body after the skeleton. Calcification of the aorta and aortic valves occurs in most individuals in westernized ...

Alzheimer's disease affects an estimated 7.2 million Americans age 65 and older, according to the Alzheimer's Association. Current tests often measure the levels of two proteins-amyloid beta (Aβ) and ...

Chung’s group captured the transition period directly by improving the time resolution of a method called single-molecule ...

For years, a protein inside our cells has quietly powered billions of dollars' worth of cancer drugs. Now a team of ...

Scientists have developed a new blood test that could spot Alzheimer’s earlier by detecting hidden changes in how proteins fold in the bloodstream.

Proteoforms, the diverse molecular variants of proteins, are key to understanding cellular functions, disease mechanisms, and ...

Every second, hundreds to thousands of molecules move through thousands of nuclear pores in each of your cells. A new high-definition view reveals the machine in action.

A newly isolated three-atom aluminum ring reveals unexpected chemistry that could help replace costly metals used in industrial reactions.

Over the past decade, however, a wave of technological advances has begun to expand the druggable proteome. These include covalent inhibitors (such as sotorasib), chemical proteomics, and AI-enabled ...