Mucus not only is an excellent physical barrier, but it also contains hydrolytic enzymes, such as lysozyme or proteases, thus representing an ... Exposure to toxicants activates a detoxifying system ...
The intricate ubiquitin-proteasome system (UPS) plays a vital role in maintaining cellular homeostasis, determining the fate of apoptotic, autophagic, necroptotic, ferroptotic, and pyroptotic ...
Erdosteine is a prodrug and metabolite I is the active metabolite of erdosteine owing to its free thiol group. In acute infective exacerbation of chronic bronchitis or chronic obstructive ...
His contributions to medicinal chemistry and bioorganic chemistry are many, particularly in the study of estrogen and androgen receptors, serine proteases and radiopharmaceuticals (see the related ...
Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, PR China CAS-HKU Joint Laboratory of Metallomics for Health and Environment, The University of Hong Kong, Pokfulam ...
The interplay between antimicrobial resistance, heavy metal pollution, and the role of microplastics
Environmental pollution with heavy metals (HMs) and microplastics (MPs) could enhance the global health challenge antimicrobial resistance (AMR). Herein, we explore the complicated mechanics of how ...
This study reports that activation of TFEB promotes lysosomal exocytosis and clearance of cholesterol from lysosomes, the strength of evidence for which is convincing with appropriate and validated ...
School of Biosciences, Faculty of Health and Medical Sciences. Professor Margaret Rayman has a doctorate in Inorganic Biochemistry from Somerville College, Oxford, and has held post-doctoral ...
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