In vertebrate retinas, specialized photoreceptors responsible for color vision (cone cells) arrange themselves in patterns ...

Filopodia have a prominent role in driving cancer cell invasion. Here, the authors show that L-type calcium channels are a druggable target regulating filopodia stability and maturation into focal ...

In Dscamb mutants, however, red cone filopodia failed to properly retract after contact with the same red cone-type and instead remained attached or even invaded the apical surface of neighboring ...

One type of higher-order assembly is the hexagonal bundle found within filopodia. A protein called fascin binds and bridges pairs of actin filaments, stitching them into bundles.

The other type of protrusion, the filopodia, are finger-like and consist of parallel, long and unbranched actin filaments.

Besides cancer cells, it is also relevant to study the importance of filopodia in other types of cells, such as embryonic stem cells and brain cells, which are highly dependent on filopodia for ...

Tiny finger-like projections called filopodia drive invasive behavior in a rare subset of lung cancer cells. Analysis of molecular features distinguishing leader from follower cells focuses on ...

Filopodia are specialized structures that extend from the cell membrane to allow a cell to explore the environment around it. These thin protrusions are full of a protein called actin, which, in ...

Besides cancer cells, it is also relevant to study the importance of filopodia in other types of cells, such as embryonic stem cells and brain cells, which are highly dependent on filopodia for their ...

Dictyostelium discoideum Diaphanous-related formin dDia2 is enriched at the tips of filopodia and interacts with profilin II and Rac1.

Credit: Alushin Lab One type of higher-order assembly is the hexagonal bundle found within filopodia. A protein called fascin binds and bridges pairs of actin filaments, stitching them into bundles.

Lamellipodia and filopodia are dynamic surface extensions of the cell which play a pivotal role in cell migration, invasion and wound healing. Biochemists from Frankfurt University have succeeded ...