ALS progressively destroys the motor neurons that control voluntary muscles. Upper motor neurons, located in the brain, send messages to lower motor neurons in the spinal cord and from there to ...

Medically reviewed by Brigid Dwyer, MD Key Takeaways Clonus causes involuntary, rhythmic muscle contractions when a muscle is stretched.It is often observed in conditions like multiple sclerosis, ...

Meeting the challenges of Huntington’s disease and upper motor neuron diseases like ALS These are exciting times for neurological disease research and the discovery of new therapeutic strategies for ...