Frontiers

A novel GCGR/GLP-1R dual-agonist TB001 ameliorates kidney fibrosis via inhibiting PERK-mediated endoplasmic reticulum stress pathway

Background: Chronic kidney disease (CKD) affects over one million individuals worldwide and remain a critical economic and healthcare burden. Renal fibrosis is the hallmark of CKD. Previous reports ...
Daily Mail

Fugitive Chinese narco kingpin dubbed 'Mr HaHa' who helped feared cartels flood US and Europe with fentanyl is captured in Cuba months after he escaped through tunnel

Zhi Dong Zhang, also wanted by the U.S., is suspected of being a 'narco-broker' with business ties to Mexico’s Sinaloa and Jalisco New Generation drug cartels, designated as 'foreign terrorist ...
C&EN

A Binding Site Competition Model for Relative Sliding of Antiparallel Microtubules Mediated by Kinesin-4 Motors and PRC1 Proteins

Key Laboratory of Soft Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China School of Physical Sciences, University of Chinese Academy of Sciences, Beijing 100049, ...
African Union

H.E. Mr. Guang Cong, the UN Special Envoy for the Horn of Africa, paid a courtesy call on AUC Chairperson

2025 Year of Reparations: Justice for Africans & People of African Descent through Reparations. 2025 Year of Reparations: Justice for Africans & People of African Descent through Reparations.