San Francisco 49ers running back Christian McCaffrey can really impact a game, and he's already getting into Mike Macdonald's ...

It appeared that San Francisco 49ers superstar Christian McCaffrey was playing in discomfort at the end of Week 17's win over ...

On the field, the guy that will be tasked with actually tackling McCaffrey most often is middle linebacker Ernest Jones IV.

Christian McCaffrey and the San Francisco 49ers head to Levi's Stadium on Saturday at 8 p.m. ET to match up with the Seattle ...

Christian McCaffrey is dealing with a stiff back ahead of Week 18. Here's the latest injury update on the 49ers RB.

Learn more about for Christian McCaffrey's prop betting lines, stats and more before his San Francisco 49ers play against the ...

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Left tackle Trent Williams has missed practice this week with a hamstring injury and has been listed as questionable to play.

Christian McCaffrey didn't practice on Tuesday, but it is nothing that will keep him out of Saturday's NFC West showdown with ...

The San Francisco 49ers practiced Tuesday without two key pieces of their offense, running back Christian McCaffrey and left ...

After being limited to just four games last season due to multiple injuries, McCaffrey has returned to top form in 2025. He’s ...

Christian McCaffrey, Trent Williams, Keion White and Kyle Juszczyk are not practicing Tuesday ahead of the 49ers’ ...