When Kerry Washington announced Demi Moore as the Golden Globes winner for Best Comedy/Musical Actress on Sunday night, the crowd reacted in surprise jubilation — and that was before The Substance star brought the house down with the best acceptance speech of the night.

Demi Moore landed the first acting award of her career — yes, career — after taking home the Golden Globe for best actress in a motion picture, musical or comedy. She won for her go-for-broke performance as an aging celebrity in the body horror satire “The Substance.