A study reveals that the immune protein IFITM3 limits flu infection severity and mutation rates, especially from zoonotic viruses. Mice without IFITM3 were more susceptible to flu infections, even ...

IFITM3 protein found to play critical role in restricting viral replication in vivo. People who carry a particular variant of the interferon-inducible transmembrane 3 (IFITM3) gene are more likely ...

Researchers have identified new roles for a protein long known to protect against severe flu infection – among them, raising the minimum number of viral particles needed to cause sickness.

Levels of IFITM3 are known to increase with age, and higher than average IFITM3 levels have been seen in some patients suffering late-onset Alzheimer’s disease.

Eight weeks after receiving their first samples of Zika virus, scientists have shown that a very small protein we all have in our bodies, interferon-induced protein 3 (IFITM3), can dramatically ...

The search for differences in IFN-sensitivity in two Zika virus lineages rules out IFITM3 as an antiviral protein against Zika virus.

This, he says, is where IFITM3 plays a crucial role. “This protein prevents the virus from ever leaving the 'compartment,'” he tells mental_floss.

Scientists have discovered that a mouse protein called IFITM3 contributes to defense against some types of viral infections by binding to an enzyme responsible for regulating the pH of a cell’s ...

They also discovered that IFITM3 is increased in a subset of late onset Alzheimer's patients, meaning that IFITM3 could potentially be used as a biomarker to identify a subset of patients who ...

Although viral replication in cardiomyocytes contributes to lethality in IFITM3 KO mice, cardiomyocyte infection is not the only cause of death.