Linear RNA is inherently unstable so using it in mRNA vaccines requires that the vaccines be stored and deployed in specific conditions to avoid degradation and loss of effectiveness, institute ...

Importantly, this synthesis persisted for an extended period, even after traditional mRNA structures began to degrade. This stability and ability to selectively target cells make Cap-circRNA an ...

Importantly, this synthesis persisted for an extended period, even after traditional mRNA structures began to degrade. This stability and ability to selectively target cells make Cap-circRNA an ...

Here we present a set of technologies in embryos and cells, including IRES-mediated translation of circular RNA (circRNA) reporters, single-molecule messenger (m)RNA isoform imaging, PacBio long-read ...

Methods: The circRNA expression profiles miRNA and mRNA data were extracted from the GEO and The Cancer Genome Atlas (TCGA) datasets, respectively. The differentially expressed (DE) RNAs were ...

U6 served as the internal standard. The reverse transcription of CircRNA and mRNA was performed with the HiScript Q RT SuperMix for qPCR Kit (Vazyme, R123-01), followed by quantification using SYBR ...

1972), including three types [microRNA (miRNA), long non-coding RNA (lncRNA), and circular RNA (circRNA)]. They can regulate biological ... and predicted the lncRNA co-expression and lncRNA-miRNA-mRNA ...