Christian McCaffrey had 107 yards from scrimmage in his season debut. The 49ers are a different team when McCaffrey is on the ...

The craziest storyline all year with the 49ers centered around Pearsall, a first-round draft pick who survived a gunshot ...

In what can be described as a miracle story, San Francisco 49ers rookie wide receiver Ricky Pearsall has made his way back ...

Former Oregon Ducks cornerback Deommodore Lenoir is now among the highest paid at his position in the National Football ...

Knox argues San Francisco 49ers safety Talanoa Hufanga could be just what the Saints defense has been missing: Injuries have ...

Cornerback Deommodore Lenoir, who has emerged as a cornerstone of the defense, agreed to a five-year extension.

San Francisco 49ers tight end George Kittle has two objectives for this season — remain healthy and win a Super Bowl.

NFL Week 11 odds, picks, predictions, TV and streaming information for the Sunday football game between the Seattle Seahawks ...

San Francisco 49ers cornerback Deommodore Lenoir has agreed to a five-year, $92 million extension to stay with the team ...

The mistakes kept piling up for the San Francisco 49ers thanks to a slew of special teams blunders, key defensive penalties ...

Kyle Shanahan’s expression said it all as Sunday’s game for the San Francisco 49ers against the Tampa Bay Buccaneers. A win ...

The San Francisco 49ers play the Tampa Bay Buccaneers on Sunday. Here's everything you need to know about how to watch.