This important study advances the HIV-1 vaccine development field by establishing six humanized immunoglobulin knock-in mouse models to facilitate the design and evaluation of HIV-1 vaccines. The ...
Neuropeptides mediate inter-tissue communication in energy metabolism, yet most remain functionally uncharacterized. Using C. elegans, we uncover a neuropeptide signaling cascade that drives lipid ...
Laboratory of Neural Computation, Institute for Quantitative Biosciences, the University of Tokyo, Tokyo, Japan Department of Life Sciences, Graduate School of Arts and Sciences, the University of ...
The authors use a modeling approach to examine the effects of local and global perturbations on the electrophysiological properties of astrocytes: their modeling results suggest that local ionic ...
We used correlative light and focussed ion beam–scanning electron microscopy (FIBSEM) to characterise the ultrastructural organisation of neuromodulatory axons in the upper layers of the adult mouse ...
This important manuscript reports exceptionally preserved, millimeter-scale segmented bilaterian microfossils from the early Cambrian Fortunian Kuanchuanpu Formation in South China. The authors ...
Lymphatic vessels beat faster as they fill with fluid through a chain of calcium signaling, though the first pressure sensor remains a mystery.
This important study combines cortex-wide activity imaging and optogenetics to characterize large-scale changes in functional connectivity following administration of the psychedelic DOI, as well as ...
In the presence of emulated cone loss, eye movements are used to gather and integrate information, leading to improved letter acuity compared to a non-moving condition.
An inTUS scientific resource is advanced to support evaluation of how low-intensity transcranial ultrasound can enhance or suppress neural function.
Diverse combinations of glutamate receptor subunits are expressed across developmental stages and even between adjacent muscles in adult Drosophila.
A biochemical approach shows co-phase separation of CCL5 with heparan sulfate establishes a specific chemokine concentration gradient for chemotactic activity.
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