In pathology-ridden layers of the cortex, synaptic genes faded while inflammation flared. In women, inflammatory and vascular pathways stood out, while neuron and oligodendrocyte disease signatures ...

Tapering. Spaghetti plots show that CSF NFL (right) rises more quickly in people with ADAD mutations (red) than in noncarriers (gray) and that this accelerates as disease progresses. In plasma (left), ...

“The astrocyte response to AD neuropathology is complex and nonlinear, both along spatial and temporal axes,” Das told Alzforum. She hopes the dataset, which is freely available online, will be a ...

Just as Eisai notches wins in its campaign for lecanemab approval around the world—last month in the European Union, this week in Mexico—a dozen research and clinical leaders called on the U.S. FDA ...

Of the 20,000+ human genes, none has greater influence on late-onset Alzheimer’s disease than APOE. But why do certain variants of this lipid transporter protect the brain, while others endanger it? A ...

Medical School: M.D. University of Illinois College of Medicine Radiology Residency: David Geffen School of Medicine at UCLA Neuroradiology Fellowship: 2-year Neuroradiology Fellowship, UCLA ...

Behold the Body. Electron microgram of a Biondi body shows a dense core surrounded by filaments that bind gold-labeled ...

Alzheimer’s disease is a long, slow neurodegenerative calamity, and scientists are still hunting for blood biomarkers that ...