In further support of that finding, the researchers determined—with the help of AI—that PHGDH plays a previously undiscovered ...

Researchers hope to launch human clinical trials in their quest for a vaccine to prevent the buildup of pathological tau after demonstrating that this vaccine generated a robust immune response in ...

University of New Mexico Health Sciences researchers hope to launch human clinical trials in their quest for a vaccine to ...

RIKEN researchers have demonstrated the protective effects of a specific genetic mutation against Alzheimer's disease in ...

A micrograph showing inflammatory responses in the cortex of the new model mouse. Alzheimer's disease patients and mouse ...

Researchers have dosed the first participant in a clinical trial of an investigational medicine designed to lower the amount of amyloid precursor ... that carries a gene pivotal to causing Alzheimer's ...

To address this question, a new study from Northwestern Medicine used modern technology, called CRISPR interference, to systematically examine every gene in the human genome ... screen to silence each ...

This external QC program comes free of charge to participating laboratories. The CSF biomarkers tau and amyloid ß (Aß) show promise as tools in the diagnostic work-up patients with suspected Alzheimer ...

Figure 1. Full activation of MGP (matrix Gla protein) requires 2 posttranslational modifications, that is, vitamin K–dependent carboxylation of glutamate at positions 2, 37, 41, 48, and 52 and serine ...

Treatment with an anti-CD47 antibody, the amyloid-β inhibitor E2609, or CD47 gene knockout significantly improved the survival rate of septic mice. Our study may provide translational opportunities ...

Describes the nature of a clinical study. Types include: Observational study — observes people and measures outcomes without affecting results. Interventional study (clinical trial) — studies new ...