In further support of that finding, the researchers determined—with the help of AI—that PHGDH plays a previously undiscovered ...

RIKEN researchers have demonstrated the protective effects of a specific genetic mutation against Alzheimer's disease in ...

A micrograph showing inflammatory responses in the cortex of the new model mouse. Alzheimer's disease patients and mouse ...

Researchers have dosed the first participant in a clinical trial of an investigational medicine designed to lower the amount of amyloid precursor ... that carries a gene pivotal to causing Alzheimer's ...

which is a precursor to Alzheimer's disease. Researchers found that people with a father with Alzheimer's disease as well as female participants had a greater spread of tau protein in the brain.

Treatment with an anti-CD47 antibody, the amyloid-β inhibitor E2609, or CD47 gene knockout significantly improved the survival rate of septic mice. Our study may provide translational opportunities ...

Copyright: © 2025 Published by Elsevier Ltd. After outlining the various cases of supposed fraudulent research, Piller alleges—really without a logical link—that ...

Background: The amyloid precursor protein (APP) is genetically associated with Alzheimer's disease (AD). Elucidating the function of APP should help understand AD pathogenesis and provide insights ...

In general, mutations causing inherited forms of the respective diseases affect the folding, aggregation and/or solubility of these proteins. In Alzheimer's disease (AD), amyloid β-protein (Aβ ...

The paper T. Liu et al., “The amyloid precursor protein is a conserved Wnt receptor,” eLife, 10:e69199, 2021. Amyloid precursor protein, which generates amyloid-β when broken down, has long been ...