which in turn launches a series of biochemical reactions within the cell. These intracellular signaling pathways, also called signal transduction cascades, typically amplify the message ...

How do these molecules activate signaling pathways in their target cells? They bind to cell-surface proteins of the seven-helix-G protein-coupled receptors (GPCRs). These in turn activate either ...

Lipids in cell membranes regulate the activity of a cancer-linked protein, cell biologists at RIKEN have discovered. This ...

CD8 + T cells accumulate in atherosclerotic plaques. LMU researchers identify a crucial signaling pathway—with therapeutic ...

Cellular signaling is an elaborate, dynamic, and interactive system of inter- and intracellular communication, responsible for governing and coordinating activities, from the basic to the complex.

In NF1, many of these medications work by blocking a specific cell signaling pathway called Ras/MAPK that is hyperactive in cells that have lost NF1 function due to gene mutation. When this signaling ...