Expanded library for drug-drug interactions (DDI): New and upgraded compound files for enzymes and transporters cover a broader range of DDI capabilities. These capabilities provide qualification ...

But Jun13296 beats the same lab's first effort on several crucial metrics. It also addresses Paxlovid’s major limitation: drug interaction-induced side effects. “Most people who are at high risk of ...

The proposed list is subject to change when new data becomes available, their rarity being a limiting factor for classification. Every day in Western countries, thousands of drugs are consumed ...

When interested in a victim drug without active metabolites, start in the left of the figure in the upper blue box. Follow the flowchart depending on the characteristics (inhibitor or inducer; ...

Based on these insights we are developing BRICHOS based biologic drugs against Alzheimer’s disease, which we are currently testing in mouse models with promising results. We are also studying ...

In terms of classification performance, both SLRF and MLRF perform fairly similarly with slight improvements in AUC and sensitivity considering MLRF especially for INH and RIF (p < 0.01). Compared to ...