Brain scan-ss-563672869 Before study initiation, NSE levels were similar for both groups. On Day 3 of the study, the NSE levels were 7.95 ± 2.86 ng/mL for the memantine group and 12.33 ± 7.09 ng ...

Among users of antidementia drugs, persons using memantine have the highest risk of pneumonia, new research shows. The use of rivastigmine patches is associated with an increased risk as well, say ...

Memantine is the first drug that targets a second neurotransmitter called glutamate. What that means — the mechanism is distinct. It has a general effect on cognition and behavior and function.

If you can target high risk patients in their late 50s or early 60s for preventative trials, it really wouldn't be before those patients reach their 80s that you could draw a long-term conclusion.

Memantine is administered orally, and appears as a fine white-to-off-white powder that is soluble in water. Since 2002, it has been available as 5- and 10-mg tablets and as an oral solution for ...

In September 2009, IQWiG concluded that no benefit has been proven for memantine in the treatment of Alzheimer's disease. An assessment now presented of twp previously unpublished studies and new ...

October 2, 2008 (Salt Lake City, Utah) — New trial data suggest that a large 28-mg, once-daily dose of memantine (Namenda, Axura, Forest Pharmaceuticals) in an extended-release formulation may ...

Discontinuing Cholinesterase When Starting Memantine Not Tied to Institutionalization Care December 3, 2024 The analysis included claims data (2014 through 2019) for 16,292 Medicare beneficiaries ...

Memantine has been used for more than a decade to treat dementia in Germany. Last year, it was approved for treatment of moderate to severe Alzheimer's in other European countries (see ARF related ...

No one knows when to take off the cholinesterase inhibitors. And although we know that the studies show effects of memantine on AD subjects with MMSE of 15 and below, we don't know "how high" to go—or ...

In particular, compared to no drug use, the combined use of Memantine and Donepezil significantly increased the probability of five-year survival by 0.05 ... high-quality medical database, ...

Memantine, a drug widely used to treat Alzheimer's disease, ... Mar. 10, 2022 — Researchers report that they found high levels of the protein Fli-1 in the brains of deceased Alzheimer's patients.