A new study reveals the dual role of MLKL in necroptosis, paving the way for new treatments for inflammatory diseases In multicellular organisms, damaged cells are systematically removed to maintain ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The necrosome is the key macromolecular ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Host cells activate cell death pathways in ...

and mixed lineage kinase domain1 like (MLKL) protein, resulting in an increase in TNFα-induced necroptosis. While this is of potential interest, it is not well integrated in the study. This potential ...

As the world’s population ages, neurodegenerative diseases are becoming more widely acknowledged as serious global health and socioeconomic issues. Although many resources have been devoted to the ...

The study presents a valuable finding on the role of cholesterol-binding sites on GLP-1 receptors although the clinical ramifications are unclear and not eminent at this point. Based on the detailed ...

Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada (C.S., K.J.R). Centre for Infection, Immunity ...

School of Life Science, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, China ...

College of Food science and Engineering, Jilin University, Changchun, Jilin 130062, China State Key Laboratory for Zoonotic Diseases, Key Laboratory for Zoonosis Research, Ministry of Education, ...