Antibodies are secreted immunoglobulin molecules produced mainly by plasma cells. The antigen-binding site of the antibody has a unique structure that allows it to bind antigen in a highly ...

Antibodies have become the Swiss Army tool for molecular biology and nanotechnology. Their outstanding ability to specifically recognise molecular antigens allows their use in many different ...

Department of Medicinal Chemistry, University of Kansas, Lawrence, United States Alzheimer Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard ...

Effects of FAD-mutant PSEN1 on endoproteolysis of C99 by γ-secretase. (A) Diagram of proteolytic cleavage of APP substrate by γ-secretase via two pathways. (B) Ribbon diagram of APP substrate bound to ...

These pages give an overview of what genes are and how they are involved in the different diseases that cause dementia. You will also find information about genetic testing for dementia. Genes ...