LEARNING POINTS Raised serum globulin concentration or total protein may be the first indication of a paraprotein, but a raised globulin level is more commonly due to polyclonally raised globulins in ...

The stage of your myeloma tells your doctor about how it is affecting you and how it might develop. Doctors use the international staging system to stage myeloma. There are 3 stages: stage 1, stage 2 ...

This advisory highlights more than 100 poster abstracts that will be presented at ASH 2025 involving researchers ...

Here, we compare the use of IgGκ/IgGλ and IgAκ/IgAλ HLC assays with conventional measurements for quantification of M-Igs and for response assessment, and evaluate the advantages and limitations of ...

The term paraproteinemic neuropathy describes a heterogeneous set of neuropathies characterized by the presence of homogeneous immunoglobulin in the serum. An abnormal clonal proliferation of ...

In this article, the IMWG’s guidelines for approaching relapsed multiple myeloma (MM) are discussed. Overall the article nicely summarizes the basic principles of IMWG’s recommendations. The ...

Some people with multiple myeloma get eye problems like blurred vision, swollen or bulging eyelids, dry or watery eyes, and even vision loss. You might hear your doctor refer to these as “ocular ...

Waldenström macroglobulinemia, a condition that most commonly occurs in lymphoplasmacytic lymphoma, typically manifests with diffuse lymphadenopathies, cytopenias, and a markedly elevated erythrocyte ...

Waldenström's macroglobulinemia is a lymphoproliferative disorder characterized by a lymphoplasmacytic bone marrow infiltrate and high levels of a monoclonal IgM in serum. 1 A number of ...

Investigators say it may soon be possible to design therapies better at staving off resistance among patients with lymphoplasmacytic lymphoma/Waldenström macroglobulinemia (LPL/WM), which is an ...