This advisory highlights more than 100 poster abstracts that will be presented at ASH 2025 involving researchers ...
LEARNING POINTS Raised serum globulin concentration or total protein may be the first indication of a paraprotein, but a raised globulin level is more commonly due to polyclonally raised globulins in ...
The stage of your myeloma tells your doctor about how it is affecting you and how it might develop. Doctors use the international staging system to stage myeloma. There are 3 stages: stage 1, stage 2 ...
The term paraproteinemic neuropathy describes a heterogeneous set of neuropathies characterized by the presence of homogeneous immunoglobulin in the serum. An abnormal clonal proliferation of ...
In this article, the IMWG’s guidelines for approaching relapsed multiple myeloma (MM) are discussed. Overall the article nicely summarizes the basic principles of IMWG’s recommendations. The ...
Activity of the NEDD8-specific inhibitor MLN 4924 in multiple myeloma and Waldenström's macroglobulinemia, and effect on miRNA expression. Background: Hyperphosphorylated paratarg-7 (pP-7) is a ...
We conducted a randomized trial of the treatment of multiple myeloma with high-dose chemotherapy followed by either one or two successive autologous stem-cell transplantations. At the time of ...
Waldenström macroglobulinemia, a condition that most commonly occurs in lymphoplasmacytic lymphoma, typically manifests with diffuse lymphadenopathies, cytopenias, and a markedly elevated erythrocyte ...
There are several reasons patients with multiple myeloma may experience the electrolyte abnormality. A new literature review assessed the causes and consequences of hypophosphatemia in patients with ...
Waldenström's macroglobulinemia is a lymphoproliferative disorder characterized by a lymphoplasmacytic bone marrow infiltrate and high levels of a monoclonal IgM in serum. 1 A number of ...
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