Innovative statistical method reveals new insights into single-cell RNA sequencing
A new statistical technique developed by a researcher at the Texas A&M University School of Public Health and colleagues ...
New method developed to relocate misplaced proteins in cells
Cells are highly controlled spaces that rely on every protein being in the right place. Many diseases, including cancers and ...
The EMBO Journal3d
A shorter splicing isoform antagonizes ZBP1 to modulate cell death and inflammatory responses
Mice express full-length protein ZBP1-L as well as an alternatively-spliced shorter isoform (ZBP1-S) containing only its two ...
Scientists discover how mutations affect calcium release channel and impact muscle disorders
The type 1 ryanodine receptor (RyR1) is an important calcium release channel in skeletal muscles essential for muscle ...
technologynetworks4d
Calcium Release Channel Mutations Impact Muscle Disease Development
Researchers uncover the dual role of the fifth transmembrane segment (S5) in the type 1 ryanodine receptor (RyR1) channel, ...
eLife5d
The Extra-Islet Pancreas Supports Autoimmunity in Human Type 1 Diabetes
In Type 1 diabetes (T1D), insulin-producing β-cells are killed by islet-infiltrating immune cells in a process called “insulitis”. T1D results in a critical requirement for exogenous insulin and ...
AZoLifeSciences on MSN6d
Membrane Tension and Calcium Signaling Regulate Phospholipid Scrambling
Researchers at the Institute for Integrated Cell-Material Sciences (WPI-iCeMS) at Kyoto University have discovered new information regarding how cells control the distribution of lipids in their cell ...