Brain-mapping technique identifies memory cells vulnerable to Alzheimer's protein buildup
Researchers from The University of Texas at Arlington and the University of California–San Francisco have used a new ...
GEN - Genetic Engineering and Biotechnology News8d
Brain Organoids Cleared of Toxic Tau Buildup by Blocking Glutamate Pathway
The results of a new study show that suppressing KCTD20, which responds to the neurotransmitter glutamate, activates a mechanism for expelling tau proteins.
ALZFORUM9d
Fragments of Tau’s Microtubule Binding Region Mess with Synapses
The fragments also directly compromise synapses they encounter along the way, according to a preprint posted February 24 on bioRxiv. Specifically, tau fragments containing the microtubule binding ...
News-Medical.Net9d
New approach to tau protein clearance offers hope for Alzheimer's treatment
USC Stem Cell scientists discover a new way to rid cells of toxic tau protein in a study involving mice and lab-grown human ...
How to clear the toxic tau protein that can lead to Alzheimer's and related diseases
The neurotransmitter glutamate is essential for regulating everything from mood to memory, but it can also encourage a toxic ...
C&EN29d
Mechanistic Insights into the Inhibitory and Destabilizing Effects of K353 Acetylation on Tau Peptides and Protofibrils
School of Physical Education, Xiangnan University, 889 Chenzhou Avenue, Chenzhou 423000, Hunan, People’s Republic of China ...
Frontiers6y
Roles of Microglial and Monocyte Chemokines and Their Receptors in Regulating Alzheimer's Disease-Associated Amyloid-β and Tau Pathologies
Chemokines and their receptors have been shown to affect amyloid-β (Aβ) and tau pathologies in mouse models of Alzheimer's disease (AD) by regulating microglia and monocyte-associated ...